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Showing posts with the label high content imaging

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SULSA Conference >Disruptive Technologies< 25. Sept. 19

September 27, 2019

cryo-elecron microscopy data analysis data visualisation high content imaging imaging iPSC malaria microscopy proteomics RNA polymeras single molecule stem cells structural biology

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John Bett: How the ubiquitin system regulates protein aggregation: implications for neurodegeneration and beyond

biochemistry genetics high content imaging HSP70 molecular biology molecular chaperones protein folding protreostasis science ubiquilin ubiquitin

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Morgan Alexander: High Throughput Materials Discovery with Polymer Microarrays

biomaterials cardiomyocytes embryonic stem cells extracellular matrix high content imaging regenerative medicine surface chemistry

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Prabhas Moghe: Parsing cellular fate-switching mechanotriggers using high content imaging

biomaterials chromatin structure epigenetics euchromatin heterochromatin high content imaging mechanobiology modelling stem cells super resolution microscopy

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Liliang Ouyang: Innovating Bioink Formulations for 3D Cell Culture and Tissue Engineering

Liliang Ouyang, Tsinghua University Innovating Bioink Formulations for 3D Cell Culture and Tissue Engineering 7.2.2024 CeMi External Seminar Hosted by Manuel Salmeron-Sanchez More about Liliang: https://llouyang.com/liliangouyang/ Some of the papers mentioned in the talk: L. Ouyang*, J.P. Wojciechowski, J. Tang, Y. Guo, M.M. Stevens*, Tunable Microgel-Templated Porogel (MTP) Bioink for 3D Bioprinting Applications , Advanced Healthcare Materials, 11, 2200027 (2022). L. Ouyang*, Pushing the Rheological and Mechanical Boundaries of Extrusion-based 3D Bioprinting . Trends in Biotechnology, 40, 891-902 (2022). Z. Fu, L. Ouyang*, R. Xu, Y. Yang, W. Sun*, Responsive Biomaterials for 3D Bioprinting: A Review . Materials Today 52, 112-132 (2022). Y. Fang, L. Ouyang, T. Zhang*, C. Wang, B. Lu, W. Sun, Optimizing Bifurcated Channels within an Anisotropic Scaffold for Engineering Vascularized Oriented Tissues . Advanced Healthcare Materials 9, 2000782 (2020). L. Ouyang, J.P.K. Armstrong, Y. ...

Joe Swift: Nuclear Lamin-A scales with tissue stiffness and enhances matrix- directed differentiation

1st of April 2015, Chichley Hall Joe Swift talked about work he did in the lab of Dennis Discher on the use of proteomics to untangle the influences that lamin mutations have on cell mechanics. Lamins are a group of proteins that line the inner aspect of the nuclear membrane. They belong to the intermediate filament family of proteins and form part of the mechanical linkage between the cytoskeleton and the DNA spooled up within the chromosomes mechanically to the cytoskeleton and thus the outside world. These proteins are responsive to the mechanical environment and the relative amount of lamin-A (a subtype) that is present within the nucleus scales with the mechanical properties of the tissue: the stiffer a tissue, the more lamin-A is present. Mutations to lamin-A that cause a range of hereditary diseases (termed laminopathies) lead to changes in the mechanical properties of nuclei, making them less resilient to the application of external forces. Jo...

2026 International Society for Mechanobiology meeting in Glasgow at SynSci

The ISMB held their biennial meeting as part of IOP's SynSci 2026 Conference in Glasgow Link to programme I attended some of the talks & will add Sketchnotes, where I am allowed to by the speaker, over the next weeks. Due to the hugely attractive alternative parallel sessions and my singular nature, I am sorry not to have been able to attend more. Monday 13.7.2026 Plenary Session Ardem Patapoutian , Howard Hughes Medical Institute, Scripps Research May the Force be with you! Piezo channels in mechanosensory biology Claire Walsh , University College London The human organ atlas as a resource for open biomedical research Patricia Osseweijer , Delft University of Technology Innovation for global justice Tuesday 14.7.2026 am Advanced Tools for Multiscale Mechanobiology Chwee Teck Lim , NUS, Mechanobiology Institute, National, University of Singapore Decoding the Mechanoresilience of Circulating Tumor Cells (link not yet live, contacted & prepped) Giuliano S...

Guillaume Salbreux: From active surfaces to evo-devo-mechanobiology

Guillaume Salbreux University of Geneva From active surfaces to evo-devo-mechanobiology Part of the Theory of Living Matter Seminar Series 19.3.25 Papers mentioned in the talk: Khoromskaia D, Salbreux G. Active morphogenesis of patterned epithelial shells . Elife 2023 Jan;12():. 10.7554/eLife.75878. 75878. Sumi, A., Hayes, P., D'Angelo, A., Colombelli, J., Salbreux, G., Dierkes, K., & Solon, J. Adherens Junction Length during Tissue Contraction Is Controlled by the Mechanosensitive Activity of Actomyosin and Junctional Recycling . Dev Cell. 2018;47(4):453-463.e3. Curran S, Strandkvist C, Bathmann J, de Gennes M, Kabla A, Salbreux G, Baum B. Myosin II Controls Junction Fluctuations to Guide Epithelial Tissue Ordering . Dev Cell. 2017;43(4):480-492.e6.

Joe Swift: Mechanobiology of cellular senescence and ageing

Joe Swift The University of Manchester Mechanobiology of cellular senescence and ageing Link to Lab webpage Papers that relate to the talk: Ageing impacts extracellular matrix turnover and remodelling in the kidney . Preston, R., Hoyle, A., Harris, A. S., Williams, E., Birtles, T., Chang, J., Swift, J., Eckersley, A. & Lennon, R., 4 Mar 2026, In: Matrix Biology Plus. 100197 Circadian and permanent pools of extracellular matrix co-exist in tendon tissue, but have distinct rates of turnover and differential responses to ageing Hoyle, A., Chang, J., Cutiongco, M. F., O’Cualain, R., Warwood, S., Knight, D., Meng, Q.-J., Kadler, K. E. & Swift, J., 10 Aug 2024, bioRxiv, p. 1-38, 38 p. Translation is an emerging constraint on protein homeostasis in ageing Llewellyn, J., Hubbard, S. J. & Swift, J., Aug 2024, In: Trends in cell biology. 34, 8, p. 646-656 11 p. Loss of regulation of protein synthesis and turnover underpins an attenuated stress response in senescent human ...

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Mathis Riehle: Family & dog - bake, whittle & draw. Research nerve repair & biomaterials, teach biology & bioengineering U of Glasgow. Views are my own - errors are mine - he/him

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