Lilach Sheiner: Knowledge gaps and opportunities in the mitochondria of the eukaryotic parasites causing toxoplasma and malaria
Lilach Sheiner: Knowledge gaps and opportunities in the mitochondria of the eukaryotic parasites causing toxoplasma and malaria
School of Molecular Bioscience external seminar
30.10.2024
Hosted by Mathis Riehle
Lilach Sheiner, University of Glasgow, School of Infection and Immunity
Link to the Sheiner lab website
Papers mentioned in the talk:
F. Silva, M., Douglas, K., Sandalli, S., MacLean, A. E.and Sheiner, L. (2023) Functional and biochemical characterization of the Toxoplasma gondii succinate dehydrogenase complex. PLoS Pathogens, 19(12), e1011867. (doi: 10.1371/journal.ppat.1011867).
MacLean, A. E., Hayward, J. A., Huet, D., van Dooren, G. G. and Sheiner, L. (2022) The mystery of massive mitochondrial complexes: the apicomplexan respiratory chain. Trends in Parasitology, 38(12), pp. 1041-1052. (doi: 10.1016/j.pt.2022.09.008).
Maclean, A. E., Bridges, H. R., F. Silva, M., Ding, S., Ovciarikova, J., Hirst, J. and Sheiner, L.(2021)Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex. PLoS Pathogens, 17(3), e1009301. (doi: 10.1371/journal.ppat.1009301).
Mühleip, A., Kock Flygaard, R., Ovciarikova, J., Lacombe, A., Fernandes, P., Sheiner, L. and Amunts, A. (2021) ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria. Nature Communications, 12, 120. (doi: 10.1038/s41467-020-20381-z).