Evangelos Giampazolias: Decoding Host Microbiome Interactions that Regulate Cancer Immunity

Evangelos Giampazolias: CRUK Manchester Institute, University of Manchester

Decoding Host Microbiome Interactions that Regulate Cancer Immunity: Killing Cancer with a Gut Instinct





SoMB External Seminar hosted by Mads Gabrielson, 6.3.2024 

THE paper discussed in the talk: Giampazolias et al. Vitamin D regulates microbiome-dependent cancer immunity Science 2024, 384: 428-437

Some of the other papers mentioned in the talk:

Lim KHJ, Giampazolias E, Schulz O, Rogers NC, Wilkins A, Sahai E, Strid J, Reis e Sousa C. (2022) Loss of secreted gelsolin enhances response to anticancer therapies. Journal for Immunotherapy of Cancer 10(9): 1-6. PubMed abstract (PMID: 36162919)

Giampazolias E, Schulz O, Lim KHJ, Rogers NC, Chakravarty P, Srinivasan N, Gordon O, Cardoso A, Buck MD, Poirier EZ, Canton J, Zelenay S, Sammicheli S, Moncaut N, Varsani-Brown S, Rosewell I, Reis e Sousa C. (2021) Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity. Cell 184(15):4016-4031.e22. PubMed abstract (PMID: 34081922)

Cell Cycle 17(3):269-270. PubMed abstract (PMID: 29169278)

Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, Roca A, Lopez J, Ichim G, Proïcs E, Rubio-Patiño C, Fort L, Yatim N, Woodham E, Orozco S, Taraborrelli L, Peltzer N, Lecis D, Machesky L, Walczak H, Albert M, Milling S, Oberst A, Ricci JE, Ryan KM, Blyth K, Tait SW. (2017) Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency.
Nature Cell Biology 19(9): 1116-1129. PubMed abstract (PMID: 28846096)

Giampazolias E, Tait SW. (2016) Mitochondria and the hallmarks of cancer.  FEBS Journal 283(5): 803-14. PubMed abstract (PMID: 26607558)