Michelle Peckham: Structure Function & Regulation of Motor Proteins: Why it is important to switch off your motor

Michelle Peckham, University of Leeds 

Structure Function & Regulation of Motor Proteins: Why it is important to switch off your motor

22.11.2023 External Seminar at the School of Molecular Biosciences, MVLS, University of Glasgow 
Hosted by Mathis Riehle
 
sketch of a scientific talk about how some motor proteins can 'self regulate' by flipping aspects of their 'tails' over teh activation area of the motor parts
sketch of a scientific talk about how some motor proteins can 'self regulate' by flipping aspects of their 'tails' over teh activation area of the motor parts AND what are affimers, what are they useful for



Some of the papers mentioned in the talk:

Carrington, Glenn, Abbi Hau, Sarah Kosta, Hannah F Dugdale, Francesco Muntoni, Adele D’Amico, Peter Van den Bergh, Norma B Romero, Edoardo Malfatti, Juan Jesus Vilchez, Anders Oldfors, Sander Pajusalu, Katrin Õunap, Marta Giralt-Pujol, Edmar Zanoteli, Kenneth S Campbell, Hiroyuki Iwamoto, Michelle Peckham, Julien Ochala: Human Skeletal myopathy myosin mutations disrupt myosin head sequestration JCI insight 8 (21)

Parker, Francine, Anna AS Tang, Brendan Rogers, Glenn Carrington, Cris Dos Remedios, Amy Li, Darren Tomlinson, Michelle Peckham: Affimers targeting proteins in the cardiomyocyte Z-disc: Novel tools that improve imaging of heart tissue. Frontiers in Cardiovascular Medicine 10, 1094563

Scarff, Charlotte A, Glenn Carrington, David Casas-Mao, Joseph M Chalovich, Peter J Knight, Neil A Ranson, Michelle Peckham Structure of the shutdown state of myosin-2. Nature 588 (7838), 515-520

Thomas G Baboolal, Gregory I Mashanov, Tatiana A Nenasheva, Michelle Peckham, Justin E Mollo: A combination of diffusion and active translocation localizes myosin 10 to the filopodial tip. Journal of Biological Chemistry 291 (43), 22373-22385

Link to a sketchnote covering an educationally slanted talk about myosin motors by Michelle at the FEBS summer school at Loch Lomond summer 2023.