Neuroimmunology Group Invited Seminar
hosted by Sue Barnett
Robin Franklin
Cambridge Neuroscience, University of Cambridge
14.12.16
More about Robin's research:
https://www.neuroscience.cam.ac.uk/directory/profile.php?rjf1000Papers that have been mentioned in the talk:
Franklin, Robin J. M. & ffrench-Constant, Charles (2017), Regenerating CNS myelin — from mechanisms to experimental medicines. Nature Reviews Neuroscience volume 18, pages 753–769
Crawford AH, Tripathi RB, Foerster S, McKenzie I, Kouioumtzidou E, Grist M, Richardson WD, Franklin RJM (2015), “Pre-existing mature oligodendrocytes do not contribute to remyelination following toxin-induced spinal cord demyelination” American Journal of Pathology 186: 511-516
Crawford AH, Tripathi RB, Richardson WD, Franklin RJM (2016), “The developmental origin of oligodendrocyte lineage cells determines their response to demyelination and susceptibility to age-associated functional decline” Cell Reports 15: 761-773
Moyon S, Dubessy AL, Aigrot MS, Trotter M, Huang JK, Dauphinot L, Potier MC, Kerninon C, Melik Parsadaniantz S, Franklin RJ, Lubetzki C (2015), “Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration.” J Neurosci35(1):4-20 Details
Ruckh JM, Zhao JW, Shadrach JL, van Wijngaarden P, Rao TN, Wagers AJ, Franklin RJ (2012), “Rejuvenation of regeneration in the aging central nervous system.” Cell Stem Cell 10(1):96-103 Details
Shen S, Sandoval J, Swiss VA, Li J, Dupree J, Franklin RJ, Casaccia-Bonnefil P (2008), “Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency.” Nat Neurosci 11(9):1024-34 Details
Woodruff RH, Fruttiger M, Richardson WD, Franklin RJ (2004), “Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination.” Mol Cell Neurosci 25(2):252-62 Details
Zhao C, Fancy SP, ffrench-Constant C, Franklin RJ (2008), “Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination.” Neurobiol Dis 31(2):209-17 Details
Zhao C, Zawadzka M, Roulois AJ, Bruce CC, Franklin RJ (2008), “Promoting remyelination in multiple sclerosis by endogenous adult neural stem/precursor cells: defining cellular targets.” J Neurol Sci 265(1-2):12-6 Details