Invited Keynote talk at the West of Scotland Surgical Association (WoSSA) Annual Surgical Meeting 30. October 2015 Glasgow
Recently published paper by the group: Genetic analysis reveals molecular subtypes of pancreatic cancer Bailey et al. Nature 531: 47–52 (2016) doi:10.1038/nature16965
More about David's work: http://www.gla.ac.uk/researchinstitutes/cancersciences/staff/davidchang/
Link to the current updated pancreatic cancer genome analysis: https://dcc.icgc.org/pcawg
Link to a blogpost that deals in detail with the paper by Nicola Wadell et al. in Nature on genomic instability of pancreatic cancers : http://scienceblog.cancerresearchuk.org/2015/02/26/pushing-unstable-pancreatic-cancers-over-the-edge/
Papers mention by David in his Talk:
Recently published paper by the group: Genetic analysis reveals molecular subtypes of pancreatic cancer Bailey et al. Nature 531: 47–52 (2016) doi:10.1038/nature16965
More about David's work: http://www.gla.ac.uk/researchinstitutes/cancersciences/staff/davidchang/
Link to the current updated pancreatic cancer genome analysis: https://dcc.icgc.org/pcawg
Link to a blogpost that deals in detail with the paper by Nicola Wadell et al. in Nature on genomic instability of pancreatic cancers : http://scienceblog.cancerresearchuk.org/2015/02/26/pushing-unstable-pancreatic-cancers-over-the-edge/
Papers mention by David in his Talk:
Waddell, N. et al. (2015) Whole genomes redefine the mutational landscape of pancreatic cancer. Nature, 518(7540), pp. 495-501. (doi:10.1038/nature14169)
Graham, J., Jamieson, N.B., Rulach, R., Grimmond, S.M., Chang, D.K., and Biankin, A.V. (2015) Pancreatic cancer genomics: where can the science take us? Clinical Genetics, 88(3), pp. 213-219. (doi:10.1111/cge.12536) (PMID:25388820).
Graham, J., Jamieson, N.B., Rulach, R., Grimmond, S.M., Chang, D.K., and Biankin, A.V. (2015) Pancreatic cancer genomics: where can the science take us? Clinical Genetics, 88(3), pp. 213-219. (doi:10.1111/cge.12536) (PMID:25388820).
Chang, D. K., Grimmond, S. M., Evans, T. R.J., and Biankin, A. V. (2014) Mining the genomes of exceptional responders. Nature Reviews Cancer, 14(5), pp. 291-292. (doi:10.1038/nrc3723)
Chantrill, L.A. et al. (2015) Precision medicine for advanced pancreas cancer: the individualized molecular pancreatic cancer therapy (IMPaCT) trial. Clinical Cancer Research, 21(9), pp. 2029-2037. (doi:10.1158/1078-0432.CCR-15-0426) (PMID:25896973)
Humphris, J., Chang, D. K., and Biankin, A. V. (2015) Inherited susceptibility to pancreatic cancer in the era of next-generation sequencing. Gastroenterology, 148(3), pp. 496-498. (doi:10.1053/j.gastro.2015.01.009) (PMID:25613311)
Alexandrov et al. [>20 authors] (2013) Signatures of Mutational Processes in Human Cancer. Nature 500(), pp415-421.(doi:10.1038/nature12477)
Alexandrov et al. [>20 authors] (2013) Signatures of Mutational Processes in Human Cancer. Nature 500(), pp415-421.(doi:10.1038/nature12477)