Sue Barnett: Heparin Sulfate a New Therapeutic in CNS Repair?

Neuroscience Seminar 24.11.2016

Prof Sue Barnett

University of Glasgow, Institute of Infection, Inflammation and Immunity




More about Sue's work: https://www.gla.ac.uk/researchinstitutes/iii/staff/susanbarnett/

Some of the papers mentioned in the talk:
Augestad, I. L., Nyman, A. K. G., Costa, A. I., Barnett, S. C., Sandvig, A., Håberg, A. K. and Sandvig, I. (2017) Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat. Neurochemical Research, 42(6), pp. 1599-1609. (doi:10.1007/s11064-016-2098-3)(PMID:28120153)

Lindsay, S. L., Toft, A., Griffin, J., Emraja, A. M.M., Barnett, S. C. and Riddell, J.(2017) Human olfactory mesenchymal stromal cell transplants promote remyelination and earlier improvement in gait co-ordination after spinal cord injury. Glia, 65(4), pp. 639-656.(doi:10.1002/glia.23117) (PMID:28144983)

O'Neill, P., Lindsay, S. L., Pantiru, A., Guimond, S. E., Fagoe, N., Verhaagen, J., Turnbull, J. E., Riddell, J. S. and Barnett, S. C. (2017)Sulfatase mediated manipulation of the astrocyte-Schwann cell interface. Glia, 65(1), pp. 19-33. (doi:10.1002/glia.23047)(PMID:27535874) (PMCID:PMC5244676)

Kiray, H., Lindsay, S. L., Hosseinzadeh, S. and Barnett, S. C. (2016) The multifaceted role of astrocytes in regulating myelination.Experimental Neurology, 283(Pt. B), pp. 541-549.(doi:10.1016/j.expneurol.2016.03.009) (PMID:26988764)(PMCID:PMC5019113)

Lindsay, S. L. and Barnett, S. C. (2016) Are nestin-positive mesenchymal stromal cells a better source of cells for CNS repair?Neurochemistry International, (doi:10.1016/j.neuint.2016.08.001)(PMID:27498150) (In Press)

Allan, D., Fairlie-Clarke, K. J., Elliott, C., Schuh, C., Barnett, S. C., Lassmann, H., Linnington, C. and Jiang, H.-R. (2016) Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system. Acta Neuropathologica Communications, 4(1), 75.(doi:10.1186/s40478-016-0344-1) (PMID:27455844)(PMCID:PMC4960877)

McCaughey, E. J., Purcell, M., Barnett, S. C. and Allan, D. B. (2016)Spinal cord injury caused by stab wounds: incidence, natural history, and relevance for future research. Journal of Neurotrauma, 33(15), pp. 1416-1421. (doi:10.1089/neu.2015.4375) (PMID:26825180)

Lindsay, S. L., Johnstone, S. A., Anthony, M., Mallinson, D. and Barnett, S. C. (2016) Comparative miRNA-based fingerprinting reveals biological differences in human olfactory mucosa and bone marrow-derived mesenchymal stromal cells. Stem Cell Reports, 6(5), pp. 729-742. (doi:10.1016/j.stemcr.2016.03.009) (PMID:27117785)(PMCID:PMC4940454)

Lindner, M. et al. (2015) Fibroblast growth factor signaling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9 environment by Fibroblast Growth Factor 9. Brain, 2015(138), pp. 1875-1893.(doi:10.1093/brain/awv102) (PMID:25907862)

Johnstone, S. A., Liley, M., Dalby, M. J. and Barnett, S. C. (2015)Comparison of human olfactory and skeletal MSCs using osteogenic nanotopography to demonstrate bone-specific bioactivity of the surfaces. Acta Biomaterialia, 13, pp. 266-276.(doi:10.1016/j.actbio.2014.11.027) (PMID:25463488)

Ioannidou, K., Edgar, J. M. and Barnett, S. C. (2015) Time-lapse imaging of glial-axonal interactions. Current Protocols in Neuroscience, 72, 2.23.1-2.23.14.(doi:10.1002/0471142301.ns0223s72) (PMID:26131661)

Donoghue, P. S., Sun, T., Gadegaard, N., Riehle, M. O. and Barnett, S. C.(2014) Development of a novel 3D culture system for screening features of a complex implantable device for CNS repair. Molecular Pharmaceutics, 11(7), pp. 2143-2150. (doi:10.1021/mp400526n)(PMID:24279373) (PMCID:PMC4087043)