Jorge Barrasa-Fano: Quantification of cell-ECM 3D forces at the fiber level

Jorge Barrasa-Fano


Ku Leuven, Be

Quantification of cell-ECM 3D forces at the fiber level


Sketchnote of Jorge Barrasa-Fano's talk on: "Quantification of cell-ECM 3D forces at the fiber level" a series of small sketches, text and boxes of teaxt, that follow the main thread of the talk interconneted by connectors



Link to MATRIX Team Webpage

Papers connected to the talk:

Investigation of mechanical forces during multicellular early angiogenic sprouting by three-dimensional traction force microscopy in hydrogel matrices.

Shapeti A, de Jong J, Barrasa-Fano J, Sanz-Herrera JA, Faurobert E, Van Oosterwyck H.Nat Protoc. 2026 Apr;21(4):1809-1835. doi: 10.1038/s41596-025-01275-0. Epub 2026 Jan 23. PMID: 41578092 

Force-mediated recruitment and reprogramming of healthy endothelial cells drive vascular lesion growth.
Shapeti A, Barrasa-Fano J, Abdel Fattah AR, de Jong J, Sanz-Herrera JA, Pezet M, Assou S, de Vet E, Elahi SA, Ranga A, Faurobert E, Van Oosterwyck H.Nat Commun. 2024 Oct 6;15(1):8660. doi: 10.1038/s41467-024-52866-6. PMID: 39370485 

J Barrasa-Fano, Apeksha Shapeti, Álvaro Jorge-Peñas, Mojtaba Barzegari, José Antonio Sanz-Herrera, Hans Van Oosterwyck
SoftwareX, Volume 15, July 2021, 100723

Advanced in silico validation framework for three-dimensional traction force microscopy and application to an in vitro model of sprouting angiogenesis.
Barrasa-Fano J, Shapeti A, de Jong J, Ranga A, Sanz-Herrera JA, Van Oosterwyck H.Acta Biomater. 2021 May;126:326-338. doi: 10.1016/j.actbio.2021.03.014. Epub 2021 Mar 15. PMID: 33737201

Guidance for 3D traction force microscopy today and in the next decade.
Barrasa-Fano J, Shapeti A, Apolinar-Fernández A, Kimps L, Smeets B, Sanz-Herrera JA, Van Oosterwyck H.Nat Methods. 2026 Mar;23(3):507-521. doi: 10.1038/s41592-025-02934-6. Epub 2025 Dec 29. PMID: 41461906