Hawa Racine Thiam: How does nuclear mechanobiology shape neutrophil functions?

Hawa Racine Thiam ORCID

Stanford University

How does nuclear mechanobiology shape neutrophil functions?

Link to Hawa Racine Thiam's lab webpage 

Papers that I thought are relevant to the talk:

Chromatin is a long-range force generator that regulates plasma membrane tension and cell integrity independently of gene expression

 View ORCID ProfileAidan T. Cabral,  View ORCID ProfileManasi Sawant,  View ORCID ProfileMinwoo Kang,  View ORCID ProfileXie Liangqi,  View ORCID ProfileHawa Racine Thiam

doi: https://doi.org/10.1101/2025.10.02.680155 BioRxiv 3.10.2025

Cellular Mechanisms of NETosis.

Thiam HR, Wong SL, Wagner DD, Waterman CM.Annu Rev Cell Dev Biol. 2020 Oct 6;36:191-218. doi: 10.1146/annurev-cellbio-020520-111016. Epub 2020 Jul 14. PMID: 32663035

NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture.

Thiam HR, Wong SL, Qiu R, Kittisopikul M, Vahabikashi A, Goldman AE, Goldman RD, Wagner DD, Waterman CM.Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7326-7337. doi: 10.1073/pnas.1909546117. Epub 2020 Mar 13. PMID: 32170015 

Link to Overview of ISMB Talks Sketchnotes, Glasgow 2026