Chris S Chen: "Forces, adhesions and vascular function"

Chris S Chen

The Wyss Institute for Biologically Inspired Engineering at Harvard University, Biomedical Engineering at Boston University

"Forces, adhesions and vascular function"

Link to lab webpage

Papers linked to the talk:

Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues.

Grzelak KA, Westerfield AD, Kumar V, Chakraborty K, Rajeeva Pandian NK, Chen CS, Bhatia SN.Adv Sci (Weinh). 2026 Jun;13(33):e18677. doi: 10.1002/advs.202518677. Epub 2026 May 10. PMID: 42107055 

The Effect of Mechanical Loading on Sprouting Angiogenesis from Engineered Macro-vessel Model.

Debbi L, Karni Katovitch O, Silverstein A, Fuchs T, Chen CS, Levenberg S.Small Methods. 2026 Feb;10(4):e00850. doi: 10.1002/smtd.202500850. Epub 2025 Aug 14. PMID: 40808483

Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option.

Uroz M, Stoddard AE, Sutherland BP, Courbot O, Oria R, Li L, Ravasio CR, Ngo MT, Yang J, Tefft JB, Eyckmans J, Han X, Elosegui-Artola A, Weaver VM, Chen CS.Nat Cell Biol. 2024 Dec;26(12):2144-2153. doi: 10.1038/s41556-024-01532-6. Epub 2024 Oct 24. PMID: 39448802 

Rapid Tissue Perfusion Using Sacrificial Percolation of Anisotropic Networks.

Lammers A, Hsu HH, Sundaram S, Gagnon KA, Kim S, Lee JH, Tung YC, Eyckmans J, Chen CS.Matter. 2024 Jun 5;7(6):2184-2204. doi: 10.1016/j.matt.2024.04.001. Epub 2024 Apr 23. PMID: 39221109

Engineered patterns of Notch ligands Jag1 and Dll4 elicit differential spatial control of endothelial sprouting.

Tiemeijer LA, Ristori T, Stassen OMJA, Ahlberg JJ, de Bijl JJJ, Chen CS, Bentley K, Bouten CVC, Sahlgren CM.iScience. 2022 Apr 27;25(5):104306. doi: 10.1016/j.isci.2022.104306. eCollection 2022 May 20. PMID: 35602952