Jon Dawson: Nanoclay gels for the delivery of regenerative micro environments

Jon Dawson 

University of Southampton

Nanoclay gels for the delivery of regenerative micro environments

CeMi Seminar invited speaker hosted by Matt Dalby 25.03.25

Genewiz sponsored this event.

The CeMi Social Media team interviewed Jon for their Podcast when he visited.  

Sketch of Jon as well as the detail of the materials and images shown during teh talk to support the message that nanoclay can help support bone repair - the main target at teh moment and where theer is hope for its application is spine repair and fusion


Link to - renovos - the nanoclay company spun out from the group

Papers mentioned in the talk:

D.M.R. Gibbs, C.R.M. Black, G. Hulsart-Billstrom, P. Shi, E. Scarpa, R.O.C. Oreffo & J.I. Dawson, (2016) Bone induction at physiological doses of BMP through localization by clay nanoparticle gels, Biomaterials, 99, 16-23.

T. Ahlfeld, Gianluca Cidonio, D. Kilian, S. Duin, A.R. Akkineni, Jonathan Dawson, Shoufeng Yang, A. Lode, Richard Oreffo & M. Gelinsky (2017) Development of a clay based bioink for 3D cell printing for skeletal application. Biofabrication, 9(3).

Daniel J. Page, Claire E. Clarkin, Raj Mani, Najeed A. Khan, Jonathan I. Dawson & Nicholas D. Evans, (2019) Injectable nanoclay gels for angiogenesis, Acta Biomaterialia, 100, 378-387

Yanghee Kim, Xia Yang, Liyang Shi, Stuart Lanham, Jons Hilborn, Richard Oreffo, Dmitri Ossipov & Jonathan Dawson (2020) Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization. Nature Communications, 11(1).

Mohamed Mousa, Yang-Hee Kim, Nicholas D. Evans, Richard O.C. Oreffo & Jon Dawson (2023) Tracking cellular uptake, intracellular trafficking and fate of nanoclay particles in human bone marrow stromal cells, Nanoscale, 15(45), 18457-18472.

Roxanna Sharon Ramnarine-Sanchez, Janos M. Kanczler, Nicholas D. Evans, Richard O.C. Oreffo & Jon Dawson (2023) Self-assembly of structured colloidal gels for high resolution 3d micropatterning of proteins at scale, Advanced Materials, 35(48).

Yanghee Kim, Gianluca Cidonio, Janos M. Kanczler, Richard O.C. Oreffo & Jon Dawson (2024) Human bone tissue-derived ECM hydrogels: controlling physicochemical, biochemical, and biological properties through processing parameters, Bioactive Materials, 43, 114-128.